Mark S. Sundrud, Ph.D.

MT Abreu, JM Davies, MA Quintero, A Delmas, S Diaz, CD Martinez, T Venables, A Reich, G Crynen, A Deshpande, DH Kerman, OM Damas, I Fernandez, AM Santander, J Pignac-Kobinger, JF Burgueno, MS Sundrud. 2021. Transcriptional behavior of regulatory T cells predicts IBD patient responses to vedolizumab therapy. IBD Journal – in press.

ML Chen, X Huang, H Wang, Y Liu, J Shang, A Eliason, C Hegner, H Park, B Frey, G Wang, DJ Kojetin, CT Weaver, ME Pipkin, DD Moore, MS Sundrud. 2021. CAR directs T cell adaptation to bile acids in the small intestine. Nature. May;593(7857):147-151. doi: 10.1038/s41586-021-03421-6. Epub 2021 Apr 7.

R Wang, S Campbell, M Amir, MA Bassette, A Eliason, MS Sundrud, TM Kamenecka, LA Solt. 2021. Genetic and pharmacological inhibition of the nuclear receptor RORa regulates TH17 driven inflammatory disorders. Nat Comm. Jan 4;12(1):76.

AR Basson, C Chen, F Sagl, A Trotter, I Bederman, A Gomez-Nguyen, MS Sundrud, S Ilic, F Cominelli, A Rodriguez-Palacios. Regulation of Intestinal Inflammation by Dietary Fats. Front Immunol. 2021 Feb 2;11:604989. doi: 10.3389/fimmu.2020.604989. eCollection 2020.

ML Chen, A Sun, W Cao, A Eliason, KM Mendez, AJ Getzler, S Tsuda, H Diao, C Mukori, NE Bruno, SY Kim, ME Pipkin, SB Koralov, MS Sundrud. 2020. Physiologic expression and function of the multidrug transporter MDR1 in cytotoxic T lymphocytes. J Exp Med. May 4;217(5):e20191388.

Y Kim, MS Sundrud, C Zhou, M Edenius, D Zocco, K Powers, EH Noss, MB Brenner, A Rao, R Mazitschek, CY Yeo, M Whitman, TL Keller. 2020. Aminoacyl-tRNA Synthetase Inhibition Activates a Novel Pathway that Branches from the Canonical Amino Acid Response in Mammalian Cells. Proc Natl Acad Sci USA. Apr 21;117(16):8900-8911. #co-first author.

A Basson , A LaSalla , G Lam , D Kulpins , E Moen , MS Sundrud , J Miyoshi , S Ilic , B Theriault , F Cominelli, A. Rodriguez-Palacios. 2020. Understanding 'artificial' mouse-microbiome heterogeneity and six actionable themes to increase study power and reproducibility. Sci Rep. Mar 19;10(1):5039.

Photo: Immunofluorescence photomicrograph demonstrating the intestinal niche of Nippostrongylus brasiliensis, a hookworm that colonizes the mouse gut and is used to model gastrointestinal nematode infections in humans. Photo Credit: Herbert laboratory, University of Pennsylvania School of Veterinary Medicine.