Chyi-Song Hsieh, MD, PhD

Yi J, Miller AT, Archambault AS, Jones AJ, Bradstreet TR, Bandla S, Hsu YS, Edelson BT, Zhou YW, Fremont DH, Egawa T, Singh S, Wu GF, Hsieh CS. Antigen-specific depletion of CD4 T cells by CAR T cells reveals distinct roles of higher and lower affinity TCRs during autoimmunity (2022). Science Immunology, in press.

Russler-Germain EV, Jung J, Miller AT, Young S, Yi J, Wehmeier A, Fox LE, Monte KJ, Chai JN, Kulkarni DH, Funkhouser-Jones LJ, Wilke G, Durai V, Zinselmeyer BH, Czepielewski RS, Greco S, Murphy KM, Newberry RD, Sibley LD, Hsieh CS. Commensal Cryptosporidium colonization drives cDC1-dependent intestinal Th1-mediated homeostasis (2021). Immunity 54(11):2547-2564. PMCID: PMC8716016

Russler-Germain EV, Yi J, Young S, Nutsch K, Wong HS, Ai TL, Chai JN, Durai V, Kaplan DH, Germain RN, Murphy KM, Hsieh CS. Gut Helicobacter Presentation by Multiple Dendritic Cell Subsets Enables Context-Specific Regulatory T Cell Generation (2021). eLife 10:e54792. PMCID: PMC7877908

Hsieh CS, Rengarajan S, Kau A, Tarazona-Meza C, Nicholson A, Checkley W, Romero K, Hansel NN. Altered IgA Response to Gut Bacteria Is Associated with Childhood Asthma in Peru (2021). J Immunol. 207(2):398-407. PMID: 34193598; PMCID: PMC8516662.

Rengarajan S, Knoop KA, Rengarajan A, Chai JN, Grajales-Reyes JG, Samineni VK, Russler-Germain EV, Ranganathan P, Fasano A, Sayuk GS, Gereau IV RW, Kau AL, Knights D, Kashyap PC, Ciorba MA, Newberry RD, Hsieh CS. A potential role for stress-induced microbial alterations in IgA-associated irritable bowel syndrome with diarrhea (2020). Cell Reports Med. 1: 100124. PMCID: PMC7659537

Rengarajan S, Vivio EE, Parkes M, Peterson DA, Roberson EDO, Newberry RD, Ciorba MA, Hsieh CS. Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease (2020). Gut Microbes 11:405.

Photo: Immunofluorescence photomicrograph demonstrating the intestinal niche of Nippostrongylus brasiliensis, a hookworm that colonizes the mouse gut and is used to model gastrointestinal nematode infections in humans. Photo Credit: Herbert laboratory, University of Pennsylvania School of Veterinary Medicine.